Ebola Virus Disease is a disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or that affects a specific location and is not simply a direct result of physical injury.

What is Ebola Virus Disease ?

Ebola Virus ailment (EVD) additionally called Ebola haemorrhagic fever(EHF) is one of the viral haemorrhagic fevers which influences someone's blood device

it is a intense, regularly deadly contamination in human beings and non human primates (monkeys, gorillas, and chimpanzees)

it's far due to infection with virus which is transmitted to people from wild animals and spreads within the human populace.

EVD is deadly in, upto- 90% of inflamed cases .

EVD outbreaks(unexpected incidence of sickness) are regarded to arise commonly in villages of principal and West Africa, close to tropical rainforests.

the most important outbreak is the continuing 2014 West Africa Ebola Outbreak, which has affected Guinea, Liberia, Sierra Leone and Nigeria. As of August 2014, greater than 1,750 cases had been suspected.

critically infected sufferers require extensive supportive care. No specific treatment or vaccine is to be had for this ailment.


history


EVD first originated in Sudan and the Democratic Republic of Congo. The ailment commonly happens in outbreaks in tropical areas of Sub Saharan Africa. Fewer than 1000 human beings were inflamed each yr from 1976 until 2013. Ebola virus turned into first detected in 1976 all through outbreak of Ebola haemorrhagic fever in Zaire and Sudan. The name of the disorder originates from one of those first recorded outbreaks in 1976 in Democratic Republic of the Congo (then Zaire), which is located at the Ebola River.

Ebola Virus Disease Symptoms

  • Fever

  • Headache

  • Weakness

  • Joint and muscle pain

  • Diarrhoea

  • Vomiting

  • Pain in stomach

  • Loss of appetite

Ebola Virus Disease Causes

EVD is as a result of 4 of five viruses in the genus Ebola virus, own family Filoviridae, order Mononegavirales. The four disorder-causing viruses in people are as follows:

Bundibugyo Ebola virus (BDBV)

Zaire Ebola virus/Ebola virus (EBOV)

Sudan Ebola virus (SUDV)

Taï forest Ebola virus (TAFV)

BDBV,EBOV,SUDV are maximum dangerous viruses as nicely accountable for causing huge range of outbreaks in Africa.

The fifth virus called Reston Ebola virus (RESTV) is known to cause ailment in non human primates (monkeys, gorillas, and chimpanzees)

Transmission

A. number one source of infection-The virus is transmitted from animals to humans. The virus is zoonotic (animal-borne) with bats being the maximum possibly reservoir of infection.

B. Secondary supply of contamination-The virus can be transmitted from human-to- human through-

Direct contact with the body fluids such as blood, sweat, saliva, semen or other body discharges of an infected man or woman.

publicity to objects like needles that have been contaminated with inflamed man or woman.

The dead body of the inflamed man or woman also can be a source of infection.

records approximately Transmission

Ebola can not be transmitted through air.

It can't be transmitted through water.

It can not be transmitted thru food.

This without a doubt states that it is not a meals-borne, water- borne and an air-borne disease.

threat of exposure

at some stage in the outbreak, the ones at better threat of infection are-

a) medical experts.

b) circle of relatives and others who are in close contact with of inflamed people.

c) Mourners who are available in direct touch with the our bodies of the deceased in burial ceremonies.

d) visitors who go to sickness susceptible regions.

Ebola Virus Disease Diagnosis

it's far hard to diagnose the ailment in early tiers of contamination as the early signs are non specific to Ebola virus infection. however, it can be recognized thru numerous lab exams which include-

Antibody-capture enzyme connected immunosorbent assay (ELISA)

Antigen detection checks

Polymerase Chain reaction(PCR)

Virus isolation by cell tradition.

Electron microscopy


Ebola Virus Disease Prevention


it's far hard to diagnose the ailment in early tiers of contamination as the early signs are non specific to Ebola virus infection. however, it can be recognized thru numerous lab exams which include-
Antibody-capture enzyme connected immunosorbent assay (ELISA)
Antigen detection checks
Polymerase Chain reaction(PCR)
Virus isolation by cell tradition.
Electron microscopy